Gad JATAU2024-06-132024-06-132023-12M.PHhttps://repository.lcu.edu.ng/handle/123456789/561COVID-19 infection in pregnant women pose a high risk of severe illness and complication, and COVID-19 vaccines have since been recommended in pregnant women after studies have shown its safety in pregnancy. Studies have shown that pregnant women in Africa show low level of COVID-19 vaccine acceptance. This study was therefore aimed at investigating the knowledge of COVID-19 vaccines among pregnant women in primary healthcare centers in Ibadan. The study was a cross-sectional survey involving 398 pregnant women. The respondents were recruited using a multistage random sampling technique and data were collected using an adapted semi–structured interviewer-administered questionnaire. With a statistical significance at p<0.05 (n = 398), It was seen that 43.0% of the respondents were between ages 21 to 35 years. 11.1% of the respondents had maximum education at the primary level. 14.1% of the respondents had at least a shot of COVID-19 vaccine during this pregnancy. 14.3% had good knowledge of the vaccine and 9% had good attitude towards COVID-19 infection. There was significant association between educational levels (p<0.001), number of children alive (p<0.001), gravity (p 0.018), parity (p <0.001), ever received any vaccine during this pregnancy (p <0.001), ever had covid-19 infection (p 0.029), knowledge (p<0.001), attitude (p<0.001) and age (p<0.001) of the respondents with COVID-19 vaccine acceptance, while there was no association between marital status (p 0.293), ethnicity (p 0.864), place of residence (p0.081), employment status (p 0.213) and co-morbidities (p 0.094) with COVID-19 vaccine acceptance. Findings reported that majority had poor attitude and knowledge of the COVID-19 vaccine with low level of COVID-19 vaccine acceptance of 47.2%. There is need for increased and continuous health education to pregnant women during antenatal care visit so as to boost their confidence in COVID-19 vaccine which will in turn lead to an increase vaccine acceptance. Key Words: COVID-19, COVID-19 vaccine, Pregnant women, Antenatal care Word Count: 299enCOVID-19COVID-19 vaccinePregnant womenAntenatal careThesis