Isolation and Characterization of Multidrug Resistant Bacteria from Pig Farms in Ibadan: One Health Approach

Simple item page
dc.contributor.authorAdeyemi Samson ABEEB
dc.date.accessioned2026-02-05T08:50:03Z
dc.date.available2026-02-05T08:50:03Z
dc.date.issued2025-12
dc.description.abstractAntibiotic resistance occurs when bacteria evolve mechanisms to withstand the antibiotics that could treat infections caused by these bacteria. The unregulated use of antibiotics contributes to the development and dissemination of MDR bacteria. Pig farms are critical in the food production chain, yet they are also potential reservoirs for multidrug resistant (MDR) bacteria. The aim of this study was to isolate and characterize multidrug resistant (MDR) bacteria isolated from samples collected on pig farms in Ibadan, utilizing the One Health approach to understand the prevalence, resistance profiles, and potential transmission pathways of these bacteria. Samples of fecal, soil, water and hand swab of the workers were collected from three pig farms in Ibadan. The analysis of the 38 samples revealed a total of 42 isolates with relatively high prevalence of both S. aureus (66%) and E. coli (50%) across various sources. The prevalence trends across sample types revealed fecal samples as the dominant source of both bacteria, particularly from farms in Ibadan North West and Egbeda local Government areas in Oyo State. The antimicrobial susceptibility testing in our study revealed high levels of resistance among both S. aureus and E. coli isolates. Notably, several isolates exhibited multidrug resistance (MDR), with Multiple Antibiotic Resistance (MAR) index values ranging from 0.3 to 0.9. MAR indices above 0.2 typically indicate high-risk sources of contamination where antibiotics are frequently used. There was also the presence of resistance genes such as bla, mecA, and qac from the isolates which were sampled. The findings of this study show the rise of antibiotic-resistant bacteria in both animal and environmental samples. The observed resistance patterns, particularly in Gram-negative and Gram-positive bacteria such as Escherichia coli and Staphylococcus aureus, have implications for public health, animal welfare, and environmental sustainability. Keywords: Pig farms, Multi drug resistant bacteria, antimicrobial resistance, Multiple Antibiotic Resistance (MAR) index Word Count: 290
dc.identifier.citationkate Turabian
dc.identifier.otherM.Sc
dc.identifier.urihttps://repository.lcu.edu.ng/handle/123456789/1288
dc.language.isoen
dc.publisherLead City University, Ibadan
dc.relation.ispartofseriesM.Sc
dc.subjectPig farms
dc.subjectMulti drug resistant bacteria
dc.subjectantimicrobial resistance
dc.subjectMultiple Antibiotic Resistance (MAR) index
dc.titleIsolation and Characterization of Multidrug Resistant Bacteria from Pig Farms in Ibadan: One Health Approach
dc.typeThesis

Files

Original bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
ABEEB Adeyemi Samson MSc Preliminary pages.pdf
Size:
1.1 MB
Format:
Adobe Portable Document Format
Download
No Thumbnail Available
Name:
ABEEB Adeyemi Samson MSc THESIS.pdf
Size:
13.3 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:
Download

Collections

Department of Biological Sciences